In the bustling landscape of medical diagnostics, QL Biotech emerges as a beacon of innovation with its state-of-the-art Typhoid Ag Rapid Test Device, now redefined as the Typhoid Rapid Test Cassette. This leading-edge diagnostic tool is engineered to transcend the conventional boundaries of typhoid fever detection, offering a swift, reliable, and user-friendly approach to identifying this prevalent disease. Typhoid fever, caused by the bacterium Salmonella typhi, poses a significant public health challenge globally, particularly in regions lacking in clean water and adequate sanitation. The early detection of typhoid is crucial for effective treatment and control of its spread, underscoring the vital role of innovative diagnostic solutions like the Typhoid Rapid Test Cassette. At the heart of the Typhoid Rapid Test Cassette lies a revolutionary lateral flow chromatographic immunoassay technology, designed to detect the presence of typhoid antigen directly from feces samples. This method not only simplifies the testing process but also significantly reduces the time required to obtain results, making it an invaluable tool in the rapid identification of the disease. The device capitalizes on the principle of immune-chromatography, where antibodies specific to the typhoid antigen are immobilized on a nitrocellulose membrane. When a feces sample is introduced to the cassette, it migrates via capillary action along the membrane, interacting with pre-applied reagents. If the typhoid antigen is present, a colored line appears, providing a clear and interpretable result within minutes.

• ASSAY PROCEDURE

  • Bring tests, specimens, buffer and/or controls to room temperature (15-30°C) before use.

    1. Specimen collection and pre-treatment: 
    1) Unscrew and remove the dilution tube applicator. Be careful not to spill or spatter solution from the tube. Collect specimens by inserting the applicator stick into at least 3 different sites of the feces. 
    2) Place the applicator back into the tube and screw the cap tightly. Be careful not to break the tip of the dilution tube. 
    3) Shake the specimen collection tube vigorously to mix the specimen and the extraction buffer. Specimens prepared in the specimen collection tube may be stored for 6 months at -20°C if not tested within 1 hour after preparation. 
    2. Testing 
    1) Remove the test from its sealed pouch, and place it on a clean, level surface. Label the test with patient or control identification. To obtain a best result, the assay should be performed within one hour. 
    2) Using a piece of tissue paper, remove the tip of the dilution tube. Hold the tube vertically and dispense 3 drops of solution into the specimen well (S) of the test device. 
    Avoid trapping air bubbles in the specimen well (S), and do not drop any solution in observation window. 
    As the test begins to work, you will see color move across the membrane. 
    3. Wait for the colored band(s) to appear. The result should be read at 10 minutes. Do not interpret the result after 20 minutes.

  
  

  INTERPRETATION OF ASSAY RESULT

  

• NOTE:

  • 1.The intensity of the color in test region (T) may vary depending on the concentration of aimed substances present in the specimen. Therefore, any shade of color in the test region should be considered positive. Besides, the substances level cannot be determined by this qualitative test.
  • 2.Insufficient specimen volume, incorrect operation procedure, or performing expired tests are the most likely reasons for control band failure.
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The utility of the Typhoid Rapid Test Cassette extends beyond its speed and accuracy. Its design is meticulously crafted to ensure ease of use, requiring minimal training for operators and making it suitable for application in a diverse array of settings, from advanced laboratory facilities to remote field locations. QL Biotech's commitment to advancing medical diagnostics manifests in this innovative solution, tailored to meet the pressing needs of rapid and reliable typhoid fever detection. By integrating the Typhoid Rapid Test Cassette into their diagnostic arsenal, healthcare providers can significantly enhance their disease management capabilities, contributing to improved patient outcomes and advancing public health efforts against typhoid fever. (Note: The above product copy is a generalized representation meant for promotional purposes. It does not delve into specific technical details or instructions related to the actual use of the product. For comprehensive information, users should consult the product manual or contact QL Biotech directly.)