The CrP Test Strip is an immunochromatographic test, based on two specific antibodies against human CrP. The concentration-dependent formation of test lines allows a rapid semiquantitative determination of CrP in whole blood samples.

The tip of the test strip is dipped into the test sample which is diluted with buffer solution. The sample now moves through the test strip from bottom to top. If the test sample contains CrP, it attaches to the first anti-CrP antibody which is conjugated with a red gold colloidal for color marking. The red CRP antibody-gold complex, together with the sample liquid, diffuses through

the membrane that is pre dispensed with lines of different amounts of the second anti-CrP antibody. The CrP-antibody-gold complex is immobilized by the antibodies coated on the membrane leading to the formation of red lines. The number of lines depends on the CrP concentration in the sample. The more CrP is contained in the sample, the more red lines become

visible.

The control line serves as a procedural control and indicates that sufficient volume of specimen has been added and membrane wicking has occurred.

• ● Internal procedural controls are included in the test. Control band appearing in the control regions is considered an internal positive procedural control, confirming sufficient specimen volume and correct procedural technique.
• ● External controls are not supplied with this kit. It is recommended that positive and negative controls be tested as a good laboratory practice to confirm the test procedure and to verify proper test performance.